November 20th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 11 | Scott Huxtable | 323 | 46 | M | Blacksburg VA | 1:27:04.2 | 6:39/M | 1:M 45-49 |
| 12 | Glen McGuire | 324 | 45 | M | Christiansburg VA | 1:27:50.4 | 6:42/M | 2:M 45-49 |
| 17 | John Turner | 231 | 48 | M | midlothian VA | 1:31:00.6 | 6:57/M | 3:M 45-49 |
| 31 | Scot Harrison | 236 | 48 | M | Roanoke VA | 1:37:14.3 | 7:25/M | 4:M 45-49 |
| 35 | Randy Clements | 352 | 45 | M | 1:37:32.2 | 7:27/M | 5:M 45-49 | |
| 40 | Samy Lamouille | 301 | 45 | M | Roanoke VA | 1:39:58.9 | 7:38/M | 6:M 45-49 |
| 42 | Brian Barckley | 343 | 49 | M | Williamsport PA | 1:40:34.6 | 7:41/M | 7:M 45-49 |
| 46 | Anthony Wattie | 321 | 45 | M | 1:41:38.2 | 7:46/M | 8:M 45-49 | |
| 52 | Chris Robertson | 94 | 48 | M | Vinton VA | 1:42:45.1 | 7:51/M | 9:M 45-49 |
| 65 | Blas Covarrubias | 346 | 46 | M | Bedford VA | 1:45:26.0 | 8:03/M | 10:M 45-49 |
| 71 | Nick Reed | 141 | 45 | M | Christiansburg VA | 1:46:32.7 | 8:08/M | 11:M 45-49 |
| 76 | Karl Kletzing | 201 | 46 | M | Roanoke VA | 1:48:54.9 | 8:19/M | 12:M 45-49 |
| 81 | John Stadnyk | 348 | 48 | M | Roanoke VA | 1:49:42.1 | 8:22/M | 13:M 45-49 |
| 95 | Eric Spangler | 125 | 49 | M | 1:52:34.9 | 8:36/M | 14:M 45-49 | |
| 96 | Kevin Caran | 254 | 47 | M | Staunton VA | 1:52:38.0 | 8:36/M | 15:M 45-49 |
| 100 | Kim Kitts | 65 | 49 | F | Christiansburg VA | 1:53:47.6 | 8:41/M | 1:F 45-49 |
| 104 | Clinton Davis | 305 | 46 | M | ROANOKE VA | 1:54:10.7 | 8:43/M | 16:M 45-49 |
| 106 | Sean Cook | 243 | 49 | M | Troutville VA | 1:54:23.6 | 8:44/M | 17:M 45-49 |
| 111 | Eduard Valeyev | 77 | 45 | M | Roanoke VA | 1:54:57.4 | 8:47/M | 18:M 45-49 |
| 122 | Alfonso Brochero | 233 | 47 | M | Roanoke VA | 1:57:27.6 | 8:58/M | 19:M 45-49 |
| 124 | Mattie Radford | 193 | 46 | F | Roanoke VA | 1:57:57.8 | 9:00/M | 2:F 45-49 |
| 135 | Ruth Woody | 250 | 47 | F | Boones Mill VA | 1:59:27.8 | 9:07/M | 3:F 45-49 |
| 140 | Kevin Slusher | 228 | 48 | M | Roanoke VA | 2:00:03.1 | 9:10/M | 20:M 45-49 |
| 161 | Shannon Ingrassia | 333 | 45 | F | Roanoke VA | 2:05:07.2 | 9:33/M | 4:F 45-49 |
| 167 | Kristofer Rau | 43 | 46 | M | Roanoke VA | 2:05:35.2 | 9:35/M | 21:M 45-49 |
| 175 | Sunshine Richards | 229 | 47 | F | Moneta VA | 2:06:09.1 | 9:38/M | 5:F 45-49 |
| 178 | Francesco Boccieri | 119 | 47 | M | 2:06:38.3 | 9:40/M | 22:M 45-49 | |
| 184 | David Oranchak | 306 | 47 | M | Roanoke VA | 2:07:38.4 | 9:45/M | 23:M 45-49 |
| 198 | Kristi Turner | 230 | 46 | F | Midlothian VA | 2:11:34.1 | 10:03/M | 6:F 45-49 |
| 208 | Tanya Leroith | 314 | 49 | F | Blacksburg VA | 2:15:25.6 | 10:20/M | 7:F 45-49 |
| 217 | Melissa Leaf | 175 | 45 | F | Roanoke VA | 2:17:19.8 | 10:29/M | 8:F 45-49 |
| 261 | Jeffery Green | 4 | 47 | M | Ocean Springs MS | 2:30:20.9 | 11:29/M | 24:M 45-49 |
| 263 | Jen Osburn | 196 | 46 | F | Salem VA | 2:31:48.0 | 11:35/M | 9:F 45-49 |
| 267 | Shannon Honaker | 255 | 45 | F | Radford VA | 2:34:20.5 | 11:47/M | 10:F 45-49 |
| 282 | Patrick Pekala | 140 | 45 | M | Roanoke VA | 2:41:18.8 | 12:19/M | 25:M 45-49 |
| 305 | Matt Trybus | 93 | 49 | M | Staunton VA | 2:59:04.5 | 13:40/M | 26:M 45-49 |
| 308 | Audrey Kern | 214 | 49 | F | Moneta VA | 3:00:54.6 | 13:49/M | 11:F 45-49 |
| 319 | Shannon Via | 218 | 47 | F | Hardy VA | 3:42:57.1 | 17:01/M | 12:F 45-49 |