May 21st, 2022
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 60 | Shannon Honaker | 532 | 45 | F | Radford VA | 30:11.3 | 9:44/M | 1/19:F 45-49 |
| 68 | Jodi Judge | 576 | 45 | F | Roanoke VA | 30:43.9 | 9:55/M | 2/19:F 45-49 |
| 72 | Tampra Scales | 682 | 45 | F | Ridgeway VA | 31:00.5 | 10:00/M | 3/19:F 45-49 |
| 73 | Dorr Booan | 595 | 47 | F | Roanoke VA | 31:18.7 | 10:06/M | 4/19:F 45-49 |
| 76 | Cheryl Shockley | 652 | 45 | F | Roanoke VA | 31:29.1 | 10:09/M | 5/19:F 45-49 |
| 81 | Christy Crouch | 724 | 49 | F | Catawba VA | 32:04.4 | 10:21/M | 6/19:F 45-49 |
| 94 | Heidi Flowers | 695 | 48 | F | Vinton VA | 33:03.4 | 10:40/M | 7/19:F 45-49 |
| 121 | Shannon Ingrassia | 592 | 45 | F | Roanoke VA | 35:30.7 | 11:27/M | 8/19:F 45-49 |
| 124 | Bridget Melvin | 570 | 46 | F | Buchanan VA | 35:45.4 | 11:32/M | 9/19:F 45-49 |
| 149 | Jessica Delgado | 703 | 46 | F | Stuart VA | 39:34.9 | 12:46/M | 10/19:F 45-49 |
| 158 | Jennifer Coburn | 688 | 48 | F | Roanoke VA | 40:07.1 | 12:56/M | 11/19:F 45-49 |
| 159 | Susan Thomas | 896 | 47 | F | Bent Mountain VA | 40:17.4 | 13:00/M | 12/19:F 45-49 |
| 161 | Angela Fisher | 517 | 48 | F | Roanoke VA | 40:34.7 | 13:05/M | 13/19:F 45-49 |
| 170 | Andrea Schwab | 612 | 46 | F | Roanoke VA | 42:19.7 | 13:39/M | 14/19:F 45-49 |
| 171 | Angela Ross | 642 | 45 | F | Copper Hill VA | 42:56.9 | 13:51/M | 15/19:F 45-49 |
| 180 | Shannon Via | 873 | 48 | F | Hardy VA | 44:00.8 | 14:12/M | 16/19:F 45-49 |
| 186 | Maricenia Desena | 981 | 46 | F | Roanoke VA | 44:52.0 | 14:28/M | 17/19:F 45-49 |
| 197 | Robyn Goodman | 710 | 49 | F | 47:14.1 | 15:14/M | 18/19:F 45-49 | |
| 225 | Dana Decker | 892 | 45 | F | Roanoke VA | 54:37.2 | 17:37/M | 19/19:F 45-49 |