January 8th, 2022
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 95 | Wendy Grider | 458 | 47 | F | Rocky Mount VA | 58:35.20 | 9:32/M | 1:F 45-49 |
| 106 | Kim Kitts | 508 | 49 | F | Christiansburg VA | 1:01:16.71 | 9:58/M | 2:F 45-49 |
| 137 | Ilona Parks | 350 | 45 | F | Roanoke VA | 1:07:27.58 | 10:58/M | 3:F 45-49 |
| 158 | Nicole Coleman | 418 | 46 | F | 1:12:26.10 | 11:47/M | 4:F 45-49 | |
| 163 | Jodi Judge | 437 | 45 | F | Roanoke VA | 1:14:34.74 | 12:08/M | 5:F 45-49 |
| 170 | Virginia Pannabecker | 534 | 45 | F | Blacksburg VA | 1:17:00.21 | 12:31/M | 6:F 45-49 |
| 182 | Amy Schoppa | 323 | 47 | F | Summerfield NC | 1:21:28.77 | 13:15/M | 7:F 45-49 |
| 191 | Shannon Honaker | 364 | 45 | F | Radford VA | 1:24:52.09 | 13:48/M | 8:F 45-49 |
| 194 | Melissa Ownby | 464 | 46 | F | Roanoke VA | 1:28:49.05 | 14:27/M | 9:F 45-49 |
| 206 | Sherry Colvin | 310 | 45 | F | Roanoke VA | 1:38:30.35 | 16:01/M | 10:F 45-49 |
| 210 | Jennifer White | 527 | 49 | F | Roanoke VA | 1:47:32.68 | 17:29/M | 11:F 45-49 |
| 212 | Giulia Toschi Gustafson | 347 | 49 | F | Salem VA | 1:56:14.62 | 18:54/M | 12:F 45-49 |