October 30th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 23 | Jaime Barcenas | 685 | 41 | M | Roanoke VA | 25:16.5 | 8:15/M | 1:M 40-44 |
| 28 | Spencer Wiegard | 966 | 43 | M | Roanoke VA | 26:04.8 | 8:26/M | 2:M 40-44 |
| 29 | Courtney Wiegard | 989 | 42 | F | Roanoke VA | 26:05.7 | 8:27/M | 1:F 40-44 |
| 31 | Grant Burks | 978 | 43 | M | Charlottesville VA | 26:16.6 | 8:35/M | 3:M 40-44 |
| 39 | Stephanie Sharpley | 918 | 43 | F | Vinton VA | 27:47.8 | 9:04/M | 2:F 40-44 |
| 41 | Erin Burks | 979 | 43 | F | Charlottesville VA | 28:00.5 | 9:08/M | 3:F 40-44 |
| 50 | Sarah Baker | 626 | 41 | F | 28:23.4 | 9:13/M | 4:F 40-44 | |
| 51 | Jodi Judge | 624 | 44 | F | Roanoke VA | 28:27.8 | 9:16/M | 5:F 40-44 |
| 60 | Joanna Gruver | 678 | 43 | F | 29:22.1 | 9:32/M | 6:F 40-44 | |
| 66 | Katie Roberts | 957 | 41 | F | Roanoke VA | 30:55.0 | 10:03/M | 7:F 40-44 |
| 70 | Shannon Honaker | 639 | 44 | F | Radford VA | 31:12.2 | 10:06/M | 8:F 40-44 |
| 98 | Keith Toppins | 658 | 44 | M | Roanoke VA | 33:58.5 | 11:09/M | 4:M 40-44 |
| 105 | Alicia Toppins | 657 | 41 | F | Roanoke VA | 35:04.9 | 11:31/M | 9:F 40-44 |
| 116 | Zak Moore | 647 | 41 | M | Roanoke VA | 37:05.9 | 12:07/M | 5:M 40-44 |
| 139 | Erin Rau | 650 | 41 | F | Roanoke VA | 39:20.1 | 12:49/M | 10:F 40-44 |
| 144 | Sadonna Sowder | 915 | 40 | F | Roanoke VA | 40:46.9 | 13:15/M | 11:F 40-44 |
| 146 | Renee Leclair | 661 | 41 | F | Roanoke VA | 40:57.3 | 13:20/M | 12:F 40-44 |
| 154 | Mary MacHae | 948 | 41 | F | 43:20.2 | 14:05/M | 13:F 40-44 | |
| 157 | Erikka Goff | 681 | 40 | F | SCOTTSVILLE VA | 43:37.4 | 14:05/M | 14:F 40-44 |
| 161 | Kendra Johnson | 693 | 44 | F | Roanoke VA | 43:53.6 | 14:20/M | 15:F 40-44 |
| 181 | Emily Keenan | 686 | 44 | F | Roanoke VA | 52:03.6 | 16:59/M | 16:F 40-44 |
| 182 | Marta Zlotnick | 682 | 44 | F | Salem VA | 52:04.6 | 16:58/M | 17:F 40-44 |
| 189 | Jen Buck | 919 | 43 | F | Roanoke VA | 57:54.3 | 18:52/M | 18:F 40-44 |
| 190 | Erica Pence | 995 | 43 | F | Vinton VA | 57:54.6 | 18:52/M | 19:F 40-44 |
| 201 | Jennifer Price | 983 | 42 | F | 1:06:59.4 | 21:46/M | 20:F 40-44 |