January 29th, 2022
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 10 | Erica Howes | 1 | 29 | F | Blacksburg VA | 1:51:37.42 | 11:10/M | 1:Open |
| 13 | Kristin Garri | 31 | 38 | F | Washington DC | 1:53:00.75 | 11:18/M | 2:Open |
| 16 | Sophie Drew | 44 | 24 | F | Blacksburg VA | 1:55:56.93 | 11:36/M | 3:Open |
| 18 | Michelle Lowry | 19 | 44 | F | Blacksburg VA | 1:57:37.15 | 11:46/M | 1:Masters |
| 30 | Heather Stokes | 4 | 37 | F | Roanoke VA | 2:12:15.58 | 13:14/M | 1:F 35-39 |
| 34 | Julie Kidd | 22 | 40 | F | Blacksburg VA | 2:25:44.69 | 14:34/M | 1:F 40-44 |
| 35 | Carin Ahner | 25 | 38 | F | Christiansburg VA | 2:25:49.59 | 14:35/M | 2:F 35-39 |
| 36 | Gemma Grove | 51 | 38 | F | Blacksburg VA | 2:29:48.04 | 14:59/M | 3:F 35-39 |
| 38 | Erica Danko | 26 | 34 | F | Roanoke VA | 2:32:08.33 | 15:13/M | 1:F 30-34 |
| 40 | Lindsey Grow | 36 | 31 | F | Roanoke VA | 2:33:59.74 | 15:24/M | 2:F 30-34 |
| 42 | Kathleen Gorman | 54 | 62 | F | Roanoke VA | 2:39:22.34 | 15:56/M | 1:F 60-64 |
| 43 | Kari Decker | 24 | 43 | F | Roanoke VA | 2:44:08.57 | 16:25/M | 2:F 40-44 |
| 44 | Katie Tokarsky | 21 | 42 | F | Roanoke VA | 2:44:17.77 | 16:26/M | 3:F 40-44 |
| 45 | Beth Johnson | 23 | 40 | F | Roanoke VA | 2:48:03.80 | 16:48/M | 4:F 40-44 |
| 47 | Mary Riley | 33 | 32 | F | Salem VA | 2:53:31.28 | 17:21/M | 3:F 30-34 |
| 48 | Lynley Golden | 38 | 20 | F | Madison Heights VA | 2:58:34.16 | 17:51/M | 1:F 20-24 |
| 49 | Virginia Pannabecker | 55 | 45 | F | Blacksburg VA | 3:00:38.89 | 18:04/M | 1:F 45-49 |
| 50 | Tracy Proffitt | 42 | 39 | F | Lynchburg VA | 3:02:01.56 | 18:12/M | 4:F 35-39 |