March 13th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 65 | Kim Kitts | 628 | 48 | F | Christiansburg VA | 1:24:15.13 | 10:02/M | 1:F 45-49 |
| 68 | Kathryn Mustard | 641 | 46 | F | Roanoke VA | 1:25:10.05 | 10:08/M | 2:F 45-49 |
| 69 | Amy Cowan | 640 | 45 | F | 1:26:09.40 | 10:15/M | 3:F 45-49 | |
| 77 | Jennifer White | 607 | 48 | F | Roanoke VA | 1:32:02.03 | 10:57/M | 4:F 45-49 |
| 101 | Melissa Ownby | 610 | 45 | F | Roanoke VA | 2:05:03.97 | 14:53/M | 5:F 45-49 |