October 30th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 6 | Scot Harrison | 943 | 48 | M | Roanoke VA | 20:15.6 | 6:33/M | 1:M 45-49 |
| 16 | Compton Biddle | 909 | 48 | M | Roanoke VA | 23:41.6 | 7:40/M | 2:M 45-49 |
| 18 | Brian Shelor | 621 | 46 | M | Salem VA | 24:00.5 | 7:46/M | 3:M 45-49 |
| 20 | Eric Spangler | 988 | 49 | M | 24:29.5 | 7:58/M | 4:M 45-49 | |
| 26 | Walter Sharpley | 998 | 46 | M | Roanoke VA | 25:44.5 | 8:24/M | 5:M 45-49 |
| 71 | Jason Shelor | 823 | 46 | M | Roanoke VA | 31:13.3 | 10:07/M | 6:M 45-49 |
| 93 | Chris Arnold | 672 | 48 | M | Roanoke VA | 33:20.8 | 10:52/M | 7:M 45-49 |
| 114 | Compton Biddle | 911 | 48 | M | Roanoke VA | 37:03.6 | 12:00/M | 8:M 45-49 |
| 117 | David Oranchak | 805 | 47 | M | Roanoke VA | 37:06.9 | 12:03/M | 9:M 45-49 |
| 130 | William Braxton | 908 | 46 | M | Roanoke VA | 38:53.8 | 12:46/M | 10:M 45-49 |
| 137 | Kristofer Rau | 649 | 46 | M | Roanoke VA | 39:19.8 | 12:49/M | 11:M 45-49 |
| 143 | Jason Burton | 625 | 48 | M | Roanoke VA | 40:27.4 | 13:10/M | 12:M 45-49 |
| 148 | David Hudson | 913 | 45 | M | Salem VA | 41:41.3 | 13:33/M | 13:M 45-49 |
| 173 | Anthony Cash | 930 | 47 | M | Roanoke VA | 49:18.0 | 18:00/M | 14:M 45-49 |
| 183 | Frank Shinault | 694 | 47 | M | Roanoke VA | 52:04.6 | 16:59/M | 15:M 45-49 |