September 4th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 2 | Alondra Moody | 4018 | 44 | F | Andersonville TN | 6:56:31.7 | 10:25/M | 1:Open |
| 6 | Stacy McMurtrey | 4017 | 43 | F | Hendersonville NC | 7:57:25.5 | 11:56/M | 2:Open |
| 10 | Claudia Guerrero Barrera | 4010 | 41 | F | Richmond VA | 8:53:10.5 | 13:20/M | 3:Open |
| 12 | Liane Jennings | 4012 | 48 | F | Johnson City TN | 8:58:30.0 | 13:28/M | 1:F 45-49 |
| 14 | Amanda Turner | 4026 | 38 | F | Morton IL | 9:25:19.4 | 14:08/M | 1:F 35-39 |
| 15 | Jennifer Deforest | 4006 | 48 | F | Callaway VA | 9:35:09.4 | 14:23/M | 2:F 45-49 |
| 20 | Elizabeth Edwards | 4007 | 45 | F | Fort Mill SC | 9:48:58.8 | 14:43/M | 3:F 45-49 |
| 28 | Alicia Malek | 4016 | 44 | F | Statesville NC | 11:10:44.6 | 16:46/M | 1:F 40-44 |