May 22nd, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 109 | Lisa Walters | 549 | 49 | F | Roanoke VA | 35:20.0 | 11:24/M | 1/4:F 45-49 |
| 125 | Maricenia Desena | 569 | 45 | F | Roanoke VA | 39:37.5 | 12:47/M | 2/4:F 45-49 |
| 155 | Susan Mathews-Duvall | 446 | 47 | F | 47:22.6 | 15:17/M | 3/4:F 45-49 | |
| 173 | Rachel Saunders | 567 | 46 | F | Roanoke VA | 57:07.3 | 18:26/M | 4/4:F 45-49 |